Monday, December 31, 2012

Alistair Overeem pokes fun at Junior dos Santos during UFC 155

Before Junior Dos Santos' bout with Cain Velasquez was over, another opponent was poking fun of the former champ. Alistair Overeem was scheduled to fight dos Santos in May, but was suspended by the Nevada Athletic Commission because of high testosterone levels before the fight.

Overeem tweeted:

Ouch! Though Overeem has a beef with dos Santos, he has to get through Antonio Silva on Feb. 2 first. Overeem applied for a license this week. He will have to appear before a hearing on Jan. 8 before he is approved.

If dos Santos and Overeem do end up fighting, it won't be for the title. Velasquez beat dos Santos in a one-sided, five-round decision on Saturday night at UFC 155.

Other popular content on the Yahoo! network:
? Y! TV: Former child stars back in the spotlight
? Sean Payton agrees to 5-year extension with Saints
? Mike Dunleavy: Coaching Nets would be ?a dream come true?
? Huge flub on Brandon McCarthy?s driver?s license

Source: http://sports.yahoo.com/blogs/mma-cagewriter/alistair-overeem-pokes-fun-junior-dos-santos-during-062228184--mma.html

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Welcome to Galaxy NGC 922... mind the black holes!

Welcome to Galaxy NGC 922... mind the black holes!Located some 150 million light-years from Earth, NGC 922 is admittedly a little far for a quick New Year's Eve getaway. But as this Hubble image reveals, the views are great, just so long as you avoid the black holes.

Situated in the constellation of Fornax, NGC 922 is home to several large black holes. At least seven of the black holes detected in the galaxy are thought to be at least ten times as massive as our Sun, which makes them quite massive for black holes of the stellar-sized class. NGC 922 is what's known as a ring galaxy, meaning that its stars are arranged in, well, a ring. And just how did that ring form? NASA explains:

NGC 922 is a ring galaxy created by the collision of a large and small galaxy about 300 million years ago. Like a rock thrown into a pond, the ancient collision sent ripples of high density gas out from the impact point near the center that partly condensed into stars. Pictured above is NGC 922 with its beautifully complex ring along the left side, as imaged recently by the Hubble Space Telescope. Observations of NGC 922 with the Chandra X-ray Observatory, however, show several glowing X-ray knots that are likely large black holes. The high number of massive black holes was somewhat surprising as the gas composition in NGC 922 ? rich in heavy elements ? should have discouraged almost anything so massive from forming.

Via NASA APOD. Click on the image up top for a closer look.

Source: http://io9.com/5972075/welcome-to-galaxy-ngc-922-mind-the-black-holes

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Violence, gangs scar Chicago community in 2012

CHICAGO (AP) ? It was February, the middle of lunch hour on a busy South Side street. The gunman approached his victim in a White Castle parking lot, shot him in the head, then fled down an alley.

The next month, one block away, also on West 79th Street: Two men in hooded sweatshirts opened fire at the Bishop Golden convenience store. They killed one young man and wounded five others, including a nephew of basketball superstar Dwyane Wade. The shooters got away in a silver SUV.

In July, a Saturday night, two men were walking on 79th when they were approached by a man who killed one and injured the other. This shooting resulted in a quick arrest; police had a witness, and a security camera caught the shooting.

These three violent snapshots of a single Chicago street are not exceptional. It's been a bloody year in the nation's third-largest city.

A spike in murders and shootings ? much of it gang-related ? shocked Chicagoans, spurred new crime-fighting strategies and left indelible images: Mayor Rahm Emanuel voicing outrage about gang crossfire that killed a 7-year-old named Heaven selling candy in her front yard. Panicked mourners scrambling as shots ring out on the church steps at a funeral for a reputed gang leader. Girls wearing red high school basketball uniforms, filing by the casket of a 16-year-old teammate shot on her porch.

A handful of neighborhoods were especially hard hit, among them Auburn-Gresham; the police district's 43 homicides (as of Dec. 21) ranked highest in the city, and represent an increase of about 20 percent over 2011. The outbreak, fueled partly by feuds among rival factions of Chicago's largest gang, the Gangster Disciples, rippled along 79th street, the main commercial drag. That single corridor offers a window into the wider mayhem that claimed lives, shattered families and left authorities scrambling for answers.

The scars aren't obvious, at first. Drive down West 79th and there's Salaam, a pristine white building of Islamic design, and The Final Call, the restaurant and newspaper operated by the Nation of Islam. Leo Catholic High School for young men. A health clinic. A beauty supply store. Around the corners, neat brick bungalows and block club signs warning: "No Littering. No Loitering. No Loud Music."

Look closer, though, and there are signs of distress and fear: Boarded-up storefronts. Heavy security gates on barber shops and food marts. Thick partitions separating cash registers from customers at the Jamaican jerk and fish joints. Police cars watching kids board city buses at the end of the school day.

Go a few blocks south of 79th to a food market where a sign bears a hand-scrawled message: "R.I.P. We Love You Eli," honoring a clerk killed in November in an apparent robbery. Or a block north to the front lawn of St. Sabina church where photos were added this year to a glass-enclosed memorial for young victims of deadly violence over the years.

Then go back to a corner of 79th, across the street and down the block from where two killings occurred, both gang-related.

There, in an empty lot, a wooden cross stands tall in the winter night. Painted in red is a plea:

"STOP SHOOTING."

___

THE TOLL: Chicago's murder count reached 500 last Friday ? the first time since 2008 it hit that mark. In 2011, there were 435 homicides. More than 2,400 shootings have occurred. Gang-related arrests are about 7,000 higher than in 2011.

___

Gang violence isn't new, but it became a major theme in the Chicago narrative this year.

Maybe it was because of the audacity of gang members posting YouTube videos in which they flashed wads of cash and guns. The sight of police brandishing automatic weapons, standing watch outside gang funerals. The sting of one more smiling young face on a funeral program. Or dramatic headlines in spring and summer, such as: "13 people shot in Chicago in 30-minute period."

It was alarming enough for President Barack Obama to mention it during the campaign, noting murders near his South Side home. Then, addressing gun violence in the aftermath of the Newtown, Conn., school shooting, he cited Chicago again.

As grim as it is, Chicago's murder rate was almost double in the early 1990s ? averaging around 900 ? before violent crime began dropping in cities across America. This year's increase, though, is a sharp contrast to New York, where homicides fell 21 percent from 2011, as of early December.

Police Superintendent Garry McCarthy says while murders and shootings are up, overall crime citywide is down about 9 percent. He says crime-fighting strategies against gangs ? some just put into place this year ? are working, but they take time.

"The city didn't get in this shape overnight," he says. "I think that we're doing ourselves a disservice by advertising a Vietnam-type body count. I've got to tell you when I speak to people ... they generally say, 'You know what? We don't even hear that anymore. It's white noise.'... The fascination unfortunately seems to be in the media and it's become a national obsession."

After the 500th homicide was reported, McCarthy released a statement saying the pace of violent crime had slowed since early 2012. Murders skyrocketed 66 percent in the first quarter of the year over the same period in 2011; by the fourth quarter, the increase had dropped to 15 percent, he said. For shootings, it was a 40 percent hike in the first quarter and 11 percent in the last quarter compared with 2011. The superintendent called the numbers "great progress."

Up to 80 percent of Chicago's murders and shootings are gang-related, according to police. By one estimate, the city has almost 70,000 gang members. A police audit last spring identified 59 gangs and 625 factions; most are on the South and West sides.

Gangs in Chicago have a long, dangerous history, some operating with the sophistication and hierarchy of corporations. In the 1980s, the leaders of the El Rukns were convicted of conspiring in a terrorism-for-hire scheme designed to collect millions from the Libyan government. Before the feds took down the leadership of the Gangster Disciples in the 1990s, the group had its own clothing line and political arm.

Nowadays, gangs are less structured and disputes more personal, says Eric Carter, commander of the Gresham district, home to 11 factions of the Gangster Disciples. "It's strictly who can help me make money," he says. "Lines have become blurred and alliances have become very fragile."

Carter says a gang narcotics dispute that started about six years ago is at the root of a lot of violence in his district.

Another change among gangs is the widespread use of YouTube, Facebook and other social media to taunt one another and spread incendiary messages. "One insult thrown on Facebook and Twitter becomes the next potential for a shooting incident on the street," Carter says.

McCarthy, who has consulted with criminologists, has implemented several plans, including an audit that identifies every gang member and establishing a long-term police presence in heavy drug-dealing areas, aimed at drying up business.

In two districts, police also have partnered controversially with CeaseFire Illinois, an anti-violence group that has hired convicted felons, including former gang members, to mediate street conflicts. McCarthy, who has expressed reservations about the organization, is taking a wait-and-see attitude.

"It's a work in progress," he says. "It hasn't shown a lot of success yet."

___

AMONG THE DEAD: An 18-year-old walking on a sidewalk. A 36-year-old at a backyard party. A 28-year-old in a car two blocks from the police station. A 40-year-old convenience store clerk, on the job just two months.

__

In a storefront on 79th, Curtis Toler has a map of the street and surrounding area with 10 stick pins. Each represents a homicide in 2012.

Toler, a former gang member, spent much of his life causing chaos. Now, he's preaching calm. As a supervisor at CeaseFire, his job is to ease tensions and defuse disputes before they explode.

Violence, he says, has become so commonplace, people are desensitized to death.

"I don't think we take it as hard as we should," he says. "When someone gets killed, there should be an uproar. But the ambulance comes, scoops them up, nobody says anything and it's back to business."

Toler's own life was shaped by guns and drugs. "In the early '90s, I was going to funerals back to back to back," he says. "When you're out there, you think you pretty much got it coming. It's a kill-or-be-killed mentality."

As he tells it, he was in a gang (in another neighborhood) from ages 9 to 30, including a six-year prison stint for involuntary manslaughter. He was shot six times, he says; he lifts a gray stocking cap pulled low over his head and presses a thumb over his right eyebrow to show the spot where a bullet struck. "I was blessed" to survive, he says, with a gap-toothed smile.

He was once so notorious, Toler says, that one day about a decade ago his grandmother returned from a community policing gathering and began crying. "She said, 'The whole meeting was about you. ... You and your friends are destroying the whole community. ... You're my grandson, but they're talking about you like you're an animal.'"

Now a 35-year-old father of four, Toler says he decided to go straight about five years ago. He knows some police don't believe his transformation. He regrets things he's done, he says, and for a time had trouble sleeping. "Life has its way of getting back at you one way or another," he says. "I believe in the law of reciprocity."

Toler's message to a new generation on the streets: I keep asking them,' What's the net worth on your life? There is no price.... You only get one. It's not a video game.'"

"You get some guys who listen," Toler says, "and some who really don't care. ... They say, 'I'm going to die anyway.'"

Two blocks east in another storefront on 79th, Carlos Nelson works to bring a different kind of stability to Gresham.

As head of the Greater Auburn Gresham Development Corp., he lures businesses to a community that despite its problems, has well-established merchants and middle-class residents who've lived here for decades.

But Nelson, a 49-year-old engineering graduate raised in Gresham, sees changes since he was a kid, most notably the easy access to guns. "These aren't six-shooters," he says. "These are automatic weapons."

Police say they've seized more than 7,000 guns in arrests this year. Strict gun control measures in Chicago and Illinois have been tossed out by federal courts, most recently the state ban on carrying concealed weapons.

Nelson says he sees limited progress despite new crime-fighting approaches. "The Chicago police department is a lot like a rat on a wheel," he says. "They're getting nowhere. They put metal detectors in the schools but they don't put that same amount of money in to educate our kids."

But Nelson also believes the problem goes beyond policing. A cultural shift is needed, he says, to break the cycle of generations of young men seeing no options.

"It's almost like the walking dead," he says. "They're emotionless about shootings or death or drugs. They think that's all that's expected of them ... that they will die or end up in jail. That's a hell of an existence. That's truly sad."

___

AMONG THE LIVING: A 17-year-old hit in the leg, wrist and foot while in a park. A 13-year-old struck in the back while riding his bicycle, A 38-year-old shot in the face while driving.

___

Cerria McComb tried to run when the bullet exploded in her leg, but she didn't get far.

Someone heard her screams, her mother says, and rushed outside to help her make a call.

"Mommy, mommy, I've been shot!" Cerria cried into the phone.

Bobbie McComb ran six blocks, her husband outpacing her. "I'm panicking," she recalls. "I can't catch my breath. All I could think of was I didn't want it to be the last time I heard her voice, the last time I saw her."

Cerria and a 14-year-old male friend were wounded. The bullet lodged just an inch from an artery in the back of Cerria's right knee, according to her mother, who says her daughter is afraid to go out since the early December shooting.

Police questioned a reputed gang member they believe was the intended target; Cerria, they say, just happened to be in the wrong place.

"I'm angry," McComb says. "I'm frustrated. I'm tired of them shooting our kids, killing our kids, thinking they can get away with it. ... If it was my son or my daughter standing out there with a gun, I would call the police on them."

A few blocks west, on 78th Place, another mother, Pam Bosley, sits at the youth center of St. Sabina Church, trying to keep teens on track. The parish is run by the Rev. Michael Pfleger, a firebrand white priest in an overwhelmingly black congregation whose crusades against violence, drugs and liquor and cigarette billboards are a staple of local news.

Bosley's 18-year-old son, Terrell, a college freshman and gospel bass player, was killed in 2006 when he and friends were shot while unloading musical equipment outside a church on the far South Side. A man charged was acquitted.

"I think about him all day and all night," Bosley says of her son. "If I stop, I'll lose my mind."

Bosley works with kids 14 to 21, teaching them life and leadership skills and ways to reduce violence. Sometimes, she says, neglectful parents are the problem; often it's gangs who just don't value life.

"You know how you have duck (hunting) season in the woods?" she asks. "In urban communities, it's duck season for us every day. You never know when you're going to get shot."

In December, Bosley phoned to console the grieving mother of Porshe Foster, 15, who was shot a few miles away while standing outside with other kids. A young man in the group has said he believed the gunman was aiming at him.

"I know how it feels to wake up in your house without your child, and you don't want to get out of bed, you don't feel like living," Bosley says.

St. Sabina is offering a $5,000 reward for information leading to an arrest. Bosley sent balloons to the girl's funeral.

On Dec. 6, hundreds celebrated the A-student who liked architecture and played on her school's volleyball and basketball teams.

Her brother, Robert, 22, says his sister "knew what was going on in the streets as well as we did," but he didn't worry because she was either at school, home or church.

"She was always a good girl," he says. "She didn't have to look over her shoulder. She was a 15-year-old girl. She didn't ever do any wrong to anybody."

___

In March, St. Sabina parishioners, led by the Rev. Pfleger, marched through the streets in protest, calling out gang factions by name. They planted the "Stop Killing" cross on 79th.

In April, the priest and other pastors returned to 79th to successfully stop the reopening of a store where there was a mass shooting; they condemned it as a haven for gangs.

In December, Pfleger stood in his church gym, watching gang members hustle down the basketball court.

On this Monday night, in this gym, it was hard to tell who was who.

The basketball teams wore different colored T-shirts with the same word: Peacemaker. They're all part of Pfleger's 12-week basketball league, aimed at cooling gang hostilities by having rivals face each other on the court. Many players, from 16 to 27, have criminal records.

The league grew out of a single successful game this fall and has high-profile supporters, including Joakim Noah of the Chicago Bulls.

Pfleger says the games have helped players build relationships, see beyond gang affiliation and stop shooting each other, at least for now.

"I have people tell me I'm naive, I'm stupid, I should be ashamed of myself working with these gangs," he says. "I could care less. We've demonized them so much we forget they're human beings."

But Pfleger also says games alone won't change anything. These young men need jobs and an education, and he's working on that.

"When there's no alternative," he says, "you'll continue to do what you do."

___

Sharon Cohen is a Chicago-based national writer. She can be reached at scohen(at)ap.org.

Source: http://news.yahoo.com/violence-gangs-scar-chicago-community-2012-174051760.html

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Video: Anchors share their New Year?s resolutions

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Source: http://video.today.msnbc.msn.com/today/50318272/

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Sunday, December 30, 2012

CV 2012 | Magistan

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Source: http://maggyzanger.com/?p=1232

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Iran: Khamenei Page Prompts Calls For Iran To Unblock Facebook

By Golnaz Esfandiari for RFE/RL

Thanks to a Facebook page in the name of Ayatollah Ali Khamenei, supporters and opponents of Iran?s supreme leader now agree on one thing: Iran should free up access to the social-networking site.

?Khorasan? last week published an opinion piece titled ?Why Don?t They Unblock Facebook?? in which the conservative daily?s editor in chief praised Khamenei?s debut on that network earlier this month.

Calling it a ?wise and smart? move by Khamenei?s office, which is believed to be behind the initiative, Mohammad Saeed Ahadian said the page was cause for Iranian officials to seriously reconsider which websites they block. He said that while exceptions should be made for sites like Facebook, which the op-ed argues could be a valuable networking tool, Iranians should be completely and permanently denied access to ?immoral? sites.

Iran

Iran

?It is illogical not to use the very suitable [platform] of the social-networking site with hundreds of millions of users to spread the profound, intelligent, and effective views of [Khamenei], and to close the door to tens of millions of people outside the country,? Ahadian wrote.

A similar argument was made within days by former Vice President Mohammad Ali Abtahi, who was jailed amid the unrest that followed Iran?s contentious 2009 presidential election.

?Western Tool?

Abtahi, an active Facebook user, said Khamenei?s Facebook presence should be welcomed. He praised it as a demonstration of the leader?s will to keep up with the modern world.

Writing on his popular blog, Abtahi said that Khamenei?s Facebook page can facilitate communication between the supreme leader and Iranians inside and outside the country, and necessitates halting any efforts to obstruct it.

That people inside Iran have to resort to antifiltering software in order to connect with Iran?s highest authority via the Internet, Abtahi writes, ?is an insult to [Khamenei] and the Iranian people.?

Similar calls have been made on Khamenei?s Facebook page itself, which since its launch on December 13 has been ?liked? by more than 20,000 people.

Khamenei supporters suggested that, if the supreme leader is on Facebook, perhaps the Iranian state should not block it. Opponents, meanwhile, argued that the Iranian establishment no longer has an excuse to filter Facebook.

?Isn?t Facebook an evil Western tool? How come Khamenei has joined it? Is he going to be arrested?? one user writes, referring the effort to counter weapons Tehran claims its enemies use in the ?soft war? being waged against the Islamic republic.

Question Of Authenticity

As recently as December 25, Iran?s Secretary of the Supreme Council of Cyberspace Mehdi Akhavan Behabadi said the authorities had no plans to unblock Facebook.

Behabadi also said Khamenei?s office had issued no statements confirming the leader?s presence on Facebook. He has suggested the page is a spontaneous move by Khamenei?s fans.

Iran observers have argued that because the link to the Facebook page and its contents were first posted on Khamenei?s Twitter account, there is little room for doubt about its authenticity.

Adding to the confusion regarding the origin and authenticity of the supreme leader?s purported social-media initiatives, Khamenei?s office has never either denied or confirmed his Facebook, Twitter, or Instagram accounts.

Facebook user Abtahi writes that, according to his investigations, Khamenei?s office is behind his Facebook page. And in his opinion piece, ?Khorasan? editor Ahadian clearly is of the view that the Facebook page was launched by the office in charge of disseminating Khamenei?s views.

Mahmood Enayat, director of the Iran Media program at the University of Pennsylvania, tells RFE/RL that the supreme leader?s image in the media is so carefully controlled that it is highly unlikely his office would allow a false Khamenei Facebook page to exist.

Deemed ?Permissible?

But Enayat does not believe the page?s existence will prompt the authorities to unblock Iranians? access to the social-networking site, which is highly popular in the country. ?The calls for the unfiltering of Facebook are likely to die out,? he says. ?The only time Iran could perhaps unblock Facebook would be around next year?s presidential vote. We have to wait and see.?

Iran restored access to Facebook a few months ahead of the 2009 presidential vote, apparently in an attempt to create a sense of freedom and win the support of young voters. But shortly afterward, amid increased use of the social-networking site by supporters of opposition candidate Mir Hossein Musavi, the site was again blocked.

Since then, many Iranians have relied on antifiltering software to gain access to Facebook.

When asked in 2011 by one of his followers about the use of Facebook, Khamenei responded that as long as it was not aimed at damaging the Islamic republic and Islam, it was fine.

?In general if it requires engaging in [immorality and evil acts] (such as spreading corruption, lies, and false materials) or if there is concern that it is sinful, or it strengthens the enemies of Islam and Muslims, it is not permissible. Otherwise it?s fine,? Khamenei wrote in a statement posted on Iranian news websites.

By launching a Facebook page for Khamenei, the Iranian establishment has essentially acknowledged the popularity of the social-networking site, which is effectively being used by opposition members to spread news and information about human rights abuses in the Islamic republic.

In the early days of its launch, Khamenei?s Facebook page became a platform for criticism of his policies. Many of the negative comments and criticism have since been removed by the page?s administrators.

About the author:

RFE RL

RFE/RL journalists report the news in 21 countries where a free press is banned by the government or not fully established.

Source: http://feedproxy.google.com/~r/eurasiareview/VsnE/~3/h3JYI3f0F6c/

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Saturday, December 29, 2012

Record set in solar cell efficiency - with the light of a thousand suns

5 hrs.

Scientists at the U.S. Department of Energy have created a solar cell that can convert 44 percent of sunlight hitting it into electrical energy, setting a new record for solar cell?efficiency. But it was only achieved by multiplying the power of the sun by nearly 1,000.

The ongoing research is being done at the III-V Multijunction Photovoltaics group at the Department of Energy's National Renewable Energy Laboratory, where the previous record of 43.5 percent was set. So while it's not a huge leap in efficiency, it's still a record.

The researchers achieve these high efficiencies by stacking multiple "junctions" into a single solar cell, each of which absorbs light at a slightly different wavelength. The "III-IV" in the name refers to the fact that the elements used?come from the third and fifth columns of the periodic table.

A new material with many desirable properties was?discovered by accident (gallium arsenide diluted with nitrogen), but proved extremely difficult to manufacture. Researchers needed to use a technique called molecular beam epitaxy to minimize impurities in the material ? but no one in the world could do it.

Solar Junction, a company started by researchers from Stanford University, decided to take up the challenge. With a few million dollars in funding, Solar Junction and NREL managed to make the new process work. The result was the "SJ3" cell, which has been breaking records ever since.

The catch is that it's not like a traditional solar cell, which simply receives sunlight on its surface and creates a modest charge from the photons. The SJ3 cell requires the power of the sun to be multiplied by special lenses, creating a beam of light hundreds of times brighter than ordinary sunlight.

In this kind of system, the power is measured in "suns": A beam 10?times brighter than the sun would be described simply as 10 suns. And?the previous efficiency record was set by a lens system that created 415 suns. The latest record was set using 947 suns.

Naturally, one may wonder if such a design is practical ? after all, how often does the sun shine a thousand times brighter than normal? But the lenses actually take normal sunlight that might have hit in a diffuse way on normal cells and concentrate it onto the more efficient SJ3 cell. So in the end it's just using the same area of sunlight in a different way.

The NREL emphasized in the report describing the record that the SJ3 design can easily replace solar systems used in satellites and other space-bound machines ? but it's lighter and more efficient, reducing rocket load and allowing for more onboard electronics.

What's next? Tweaking the design to include a germanium layer used previously could raise efficiency as high as 50 percent ? definitely?a major landmark in solar power, if researchers?can achieve it, although applying it to everyday power needs is another project?altogether.

Information on other research being done by the NREL, including other forms of solar cells and systems, can be found at their webpage. More technical details about the SJ3 cell are in?the NREL article describing the record.

Devin Coldewey is a contributing writer for NBCNews Digital. His personal website is?coldewey.cc.

Source: http://www.nbcnews.com/technology/technolog/record-set-solar-cell-efficiency-light-thousand-suns-1C7753189

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Search Engine Land's Most Popular Stories On Google+ In 2012 ...

It?s started, the top lists of 2012! Over the next few days, we?ll be posting a series of these, including the most read Search Engine Land stories, the most tweeted ones and the ones most liked on Facebook. But to kick it off, the stories with the most +1?s on Google+.

How did we collect this data? Search Engine Land columnist?Annie Cushing?suggested we use Social Crawlytics, a tool that easily crawls the site and reports on the social activity for each URL. If you haven?t checked it out, go do so. It?s free to get started.

A few observations while aggregating list:

  • Seventeen of the top 20 stories have the word ?Google? in the headline. People on Google+ sure like stories about Google!
  • Eight of these stories have the word ?Panda? in the headline, so Google?s Panda Update that began in 2011 made news all through 2012
  • Three stories mention ?SEO? in the headline

Without further ado, here are our top stories with the most +1?s from 2012, with the number of +1?s each received shown after the headline:

1. Google Confirms Panda 3.3 Update, Plus Changes To How It Evaluates Links, Local Search Rankings & Much More?(490)

2. Google Launches Knowledge Graph To Provide Answers?(336)

3. Google Pushing Out Panda Update 3.9 Tonight?(278)

4. The Definitive Guide To Google Authorship Markup?(268)

5. Official: It?s Google Panda Update 23, Impacting ~1.3% Of Queries?(266)

6. For Social Media Marketers, SEO Is Much More Popular Than PPC?(263)

7. Google Releases Panda Update 21, Impacts 1.1% Of US Queries In English?(234)

8. WSJ Says Big Google Search Changes Coming? Reality Check Time!?(231)

9. Back To The Future: Google Announces A Meta Keywords Tag Just For News Articles?(229)

10. Google Panda 3.2 Update Confirmed?(213)

11. Ex-Googler: ?To Please Google With Your SEO, Forget About SEO??(208)

12. Google Panda Update 20 Released, 2.4% Of English Queries Impacted?(206)

13. Google Places Ranking Factors ? The PhD Version?(194)

14. Facebook Gets Into Local Search With ?Facebook Nearby? For iOS & Android?(172)

15, Google Says Panda 3.4 Is ?Rolling Out Now??(170)

16. Panda Update 3.92 Rolling Out (Or Is It Panda 20 Time?)?(161)

17. Google?s Gags Go Worldwide For April Fool?s Day 2012?(155)

18. 2012 Year In Review: Important Shifts In Google SEO?(144)

19. Study: 39% Of Google Search Referrers Now ?Not Provided??(142)

20. Google Plus Connections Are The New Links?(126)

Related Topics: Most Popular Stories | Top News



SMX - Search Marketing Expo

Source: http://searchengineland.com/most-popular-stories-on-google-143594

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French panel overturns 75 percent tax on ultrarich

PARIS (AP) ? A French constitutional panel has thrown out a plan to tax the ultrawealthy at a 75 percent rate, saying it was excessive.

The constitutional council ruled Saturday that the highly contentious tax, which President Francois Hollande promised to impose while campaigning, was unfair. It was intended to hit those with incomes over ?1 million ($1.32 million).

The French government approved the tax in its most recent budget, but even before many said it would do little to stem the country's mounting fiscal problems and would drive away the wealthiest citizens. Hollande's popularity, meanwhile, has been tanking as the country's unemployment continued its rise for the 19th straight month.

In recent weeks, Gerard Depardieu ? France's most famous actor ? moved to Belgium to avoid his home country's high taxes.

Source: http://news.yahoo.com/french-panel-overturns-75-percent-tax-ultrarich-104117363--finance.html

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Senate approves $60.4 billion Sandy aid bill

(AP) ? The Senate on Friday approved a $60.4 billion emergency spending aid package for victims of Hurricane Sandy that had been backed by Senate Democrats.

Democrats had to turn back Republican efforts to cut programs such as $150 million in fisheries aid that Republican lawmakers said was unrelated to the storm that hammered the East Coast late in October. The measure cleared the Senate on a 62-32 vote, with 12 Republicans supporting the bill. Sen. Mark Pryor, D-Ark., was the only Democrat to vote against the bill, but he later switched his vote to support the measure.

The bill faces uncertain prospects in the House, where GOP leaders appear reluctant to move quickly on a big spending bill in the final days of a lame duck session. Congress' attention is focused on talks over the so-called fiscal cliff of tax hikes and automatic spending cuts.

Sandy was blamed for at least 120 deaths and battered coastline areas from North Carolina to Maine. New York, New Jersey and Connecticut were the hardest hit states and suffered high winds, flooding and storm surges. Sandy damaged or destroyed more than 72,000 homes and businesses in New Jersey. In New York, 305,000 housing units were damaged or destroyed and more than 265,000 businesses were affected.

Senate Republicans failed on an amendment for a smaller package of about $24 billion in aid for Sandy, which was the most costly natural disaster since Hurricane Katrina in 2005 and one of the worst storms ever in the Northeast.

House GOP leaders have not said how they plan to proceed. But House Appropriations Committee Chairman Hal Rogers of Kentucky has said Congress should probably begin with a smaller aid package for immediate recovery needs and wait until more data can be collected about storm damage before approving additional money next year.

Rep. Paul Ryan, the 2012 GOP vice presidential nominee and a leading House fiscal conservative, has criticized the Democratic bill as "packed with funding for unrelated items, such as commercial fisheries in American Samoa and roof repair of museums in Washington, D.C."

Sen. Charles Schumer, D-N.Y., urged House leaders to "put this bill on the floor quickly and allow a vote." If the House balks, Schumer said, the Senate bill provides "very good groundwork" for seeking Sandy aid next year.

The measure includes $11.5 billion for the Federal Emergency Management Agency's chief disaster relief fund and $17 billion for community development block grants, much of which would help homeowners repair or replace their homes. Another $11.7 billion would help repair New York City's subways and other mass transit damage and protect them from future storms. Some $9.7 billion would go toward the government's flood insurance program. The Army Corps of Engineers would receive $5.3 billion to mitigate flood future risks and rebuild damaged projects.

Senate Republicans said much of the spending in the Democratic bill was for projects unrelated to Sandy, such as $150 million for fisheries disasters that could go to Alaska as well as Gulf Coast and New England states. Sen. Tom Coburn, R-Okla., sought to strip the fisheries funding, but his amendment failed.

To court votes, Democrats last week broadened some of their bill's provisions to cover damage from Hurricane Isaac, which struck the Gulf Coast earlier this year. A provision was added to the $2.9 billion allotted to Army Corps of Engineers projects to reduce future flooding risks; the coverage area for that program will now include areas hit by Isaac in addition to Sandy. Democrats also shifted $400 million into a community development program for regions suffering disasters, beyond areas struck by Sandy.

A Coburn amendment to reduce the federal share of costs for the Army Corps of Engineer projects to reduce future flooding risks also failed.

Most of the money in the $60.4 billion bill ? $47.4 billion ? is for immediate help for victims and other recovery and rebuilding efforts. The aid is intended to help states rebuild public infrastructure like roads and tunnels, and help thousands of people displaced from their homes.

"It will actually put people to work in their own communities, rebuilding their own communities," said Sen. Barbara Mikulski, D-Md., who chairs the Senate Appropriations Committee.

GOP Sens. John McCain of Arizona and Coburn, two frequent critics of government spending, targeted what they called "questionable" spending in the Democratic bill, including $2 million for roof repairs at Smithsonian Institution museums and $58 million in subsidies for tree planting on private properties. A McCain amendment to strip the tree subsidies failed.

Republicans also criticized $13 billion in the Democratic bill for projects to protect against future storms, including fortifying mass transit systems in the Northeast. Republicans said however worthy such projects may be, they are not urgently needed and should be considered by Congress in the usual appropriations process next year.

The Congressional Budget Office has estimated that only about $9 billion of the $60.4 billion proposed by Democrats would be spent over the next nine months. The Democratic bill included many large infrastructure projects that often require years to complete, but Republicans said the CBO estimate of such drawn-out spending undercuts the urgency of the Democrats' aid package.

More than $2 billion in federal funds has been spent so far on relief efforts for 11 states and the District of Columbia. FEMA's disaster relief fund still has about $4.3 billion, and officials have said that is enough to pay for recovery efforts into early spring.

New York, New Jersey, Connecticut, District of Columbia, West Virginia, Virginia, Maryland, New Hampshire, Delaware, Rhode Island, Pennsylvania and Massachusetts are receiving federal aid.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2012-12-28-Superstorm%20Aid/id-1a0bdcc4471b4a22870bfdf09243ad84

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Spain does not need European help for now, says PM

MADRID (Reuters) - Spanish Prime Minister Mariano Rajoy said on Friday that Spain did not need to tap for now the European Central Bank's bond-buying program for troubled euro zone governments but did not rule out asking for aid in the future.

Rajoy has faced pressure from Spain's international partners -- including the European Commission, the European Central Bank (ECB) and the International Monetary Fund (IMF) -- to seek a European Union bailout. He has resisted so far, helped by an easing of the euro zone debt crisis.

"We are not thinking of asking the European Central Bank to intervene and buy bonds in the secondary market," he said at a news conference in Madrid. "But we can't rule it out in the future."

Rajoy has been able to delay a rescue because the ECB's pledge to intervene in the market and support Spanish bond prices has brought down Spain's borrowing costs since the summer.

He praised the ECB's move on Friday.

"I think it has been a very significant decision. It has had a calming effect on the markets," he said.

But Rajoy's delaying tactics are risky at a time when the Spanish economy is contracting sharply, with 25 percent unemployment. Some market commentators believe Spain's finances could spiral into chaos if it is forced to seek a bailout due to a sudden deterioration in bond markets.

Spain's country risk, the premium bondholders demand to buy Spanish 10-year benchmark bonds over German benchmarks, was around 400 basis points on Friday, well off highs of above 600 in July.

Rajoy warned Spaniards of a tough year ahead, especially the first half, but said he hoped to see some improvement in the second half of 2013.

(Reporting by Sonya Dowsett and Clare Kane; Editing by Roger Atwood)

Source: http://news.yahoo.com/spains-pm-says-does-not-rule-asking-european-131704101--finance.html

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Monday, December 24, 2012

What a call to courage sounds like: Woody Guthrie?s ?Union Maid? (Americablog)

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Surprise! Social media companies are businesses too - Digital Trends

Instagram behaving badly social networks

As the Instagram fallout continues, users need to examine the source of our hurt: Are social networks really expected to have our backs? Maybe it's time to put down the pitchfork.

This week, the latest social network to feel users? wrath was Instagram. The photo-sharing platform?s terms of service and privacy policy update inspired a rage so real (can we call it #Instagate yet?) that CEO Kevin Systrom issued something of a backpedal (a weak one, but nonetheless, a backpedal) and a soft apology.

instagate sell outs?I?m writing this today to let you know we?re listening and to commit to you that we will be doing more to answer your questions, fix any mistakes, and eliminate the confusion,? he wrote. ?As we review your feedback and stories in the press, we?re going to modify specific parts of the terms to make it more clear what will happen with your photos.?

A very nice (if vague) sentiment. What?s more interesting was this line:

?From the start, Instagram was created to be a business.?

Because apparently, we all forgot that ? we forget it every time a social network acts like a business. ?Acts like a business? isn?t even the right thing to say, because they are businesses. When Facebook switched to the Timeline and later announced its IPO, users screamed foul. When Twitter announced API restrictions, it was labeled a sellout. The Tumblr-devoted have had some not so nice things to say about their beloved platform?s advertising strategies.

And it?s not just when these social networks do something that leverages our data (although this is the more appropriate time for us to get mad, but I?ll get to that), it?s when they grow up a little and we feel left behind. Facebook was originally a place made by a college kid for college kids ? and we, the early users, identified with that. It was acceptable to litter the place with photo proof of our drunken antics and moody status updates about our boyfriends. It felt like it was ours. Twitter was an international communication wire, where the earliest tweeters were swept up in building this thing? as it was being built by the development team ? users, in fact, are responsible for the hashtag?s purpose.

We identified with these networks and their creators. It wasn?t Microsoft or Intel or even Google making these places for us to store our digital lives, people were creating them. People with names and faces and lives that the average person knows, something that can?t be said for entrepreneurs of yesteryear. Everybody knows who Mark Zuckerberg is, and plenty of people have at least some awareness of who Biz Stone, Jack Dorsey, Kevin Rose, David Karp, and Kevin Systrom are. This isn?t how it used to work in the computing and digital world (before anyone yells at me, I do acknowledge exceptions like Paul Allen, Bill Gates, and Steve Jobs). But now we do, and for the most part, they are people that used to be a lot like us. And now, they?re not. They?re big time, world-known, extremely rich enterprise heads leading million and billion dollar companies. And that makes it easy to call them sell outs.

The business of social networking is tricky. It is anything but finite. There are still so many unknowns ? this book is being written as we go along, and we, the users are helping write it. Which is where more of the hurt comes in. When Instagram said it could use our images for advertising purposes (the extent of which was admittedly less than we first thought, but still), there was a visceral reaction for a reason. It felt like the very person who gave us the camera just opened our high school locker and ripped off all the photos lining the inside. We create and experience memories in different ways than we used to, much of it is happening online now, via social networks ? and they were created with the intention of evoking this emotion out of us. And so when those social networks do anything with these nostalgic status updates, these cherished photos, these personal check-ins other than sit back and allow us to digitally scrapbook away, we get angry.

Here?s the thing: We can?t anymore. Maybe a couple of years ago we could, but ignorance is no longer bliss. You don?t have to like what social networks are doing with your data (or will do with you data ? it will be leveraged, eventually; it will all be leveraged. Trust.) But you do have to accept it ? if you want to use them, that is. If a social platform wants to be successful and iterate at the pace and feature push we?ve become accustomed to, it has to make money. It?s a necessary evil and it?s a price we?ll have to pay to use most of them. The days of social networking innocence were short and they are gone. Now, for better or worse, it?s nothing personal ? it?s just business.?

Source: http://www.digitaltrends.com/social-media/why-we-get-mad-at-social-networks-a-businesses/

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Rebels threaten to storm 2 Syrian Christian towns

BEIRUT (AP) ? Rebels have threated to storm two predominantly Christian towns in central Syria, saying regime forces are using them to attack nearby areas, an activist group said Saturday. It says such an attack could force thousands of Christians from their homes.

Russia's foreign minister, meanwhile, said that Damascus has consolidated its chemical weapons into one or two locations to protect them from a rebel onslaught.

Concerns over Syria's chemical arsenal have escalated as the regime of President Bashar Assad suffers losses on the battlefield. U.S. intelligence officials have said the regime may be readying chemical weapons and could be desperate enough to use them, while both Israel and the U.S. have also expressed concerns they could fall into militant hands if the regime crumbles.

Moscow's Foreign Minister Sergey Lavrov said Russia, which has military advisers training Syria's military, has kept close watch over Damascus's chemical arsenal. He said the Syrian government has moved them from many arsenals to just "one or two centers" to properly safeguard them.

Lavrov also told reporters on a flight from an EU summit late Friday that countries in the region had asked Russia to convey an offer of safe passage to Assad.

Syria refuses to confirm or deny if it has chemical weapons but Damascus is believed to have nerve agents as well as mustard gas. It also possesses Scud missiles capable of delivering them.

Meanwhile, the Britain-based Syrian Observatory for Human Rights reported that one rebel group has issued an ultimatum to the towns of Mahrada and Sqailbiyeh in the province of Hama.

A video released by rebels showed Rashid Abul-Fidaa, who identified himself as the Hama commander of the Ansar Brigade, calls on residents to "evict" regime forces or be attacked.

"Assad's gangs in the cities are shelling our villages with mortars and rockets destroying our homes, killing our children and displacing our people," said Abdul-Fidaa, who wore an Islamic headband and was surrounded by gunmen. "You should perform your duty by evicting Assad's gangs," he said. "Otherwise our warriors will storm the hideouts of the Assad gangs."

He accused regime forces of taking positions in the two towns in order to "incite sectarian strife" between Christians and the predominantly Sunni opposition. Assad belongs to the Alawite minority sect, an off-shoot of Shiite Islam.

Mahrada was the hometown of Ignatius Hazim, the former Patriarch of the Damascus-based Eastern Orthodox Church who passed away on Dec. 5 at the age of 92.

Christians, who make up about 10 percent of Syria's population, say they are particularly vulnerable to the violence sweeping the country of 22 million people. They are fearful that Syria will become another Iraq, with Christians caught in the crossfire between rival Islamic groups.

The conflict started 21 months ago as an uprising against Assad, whose family has ruled the country for four decades. It quickly morphed into a civil war, with rebels taking up arms to fight back against a bloody crackdown by the government. According to activists, more than 40,000 people have been killed since March 2011.

Clashes between troops and rebels in the central city of Homs, Syria's third largest, have already displaced tens of thousands of Christians, most of whom either fled to the relatively safe coastal areas or to neighboring Lebanon.

Rami Abdul-Rahman, who heads the Observatory, said some Christians and Alawites have also left Hama province in the past several days to escape violence. He said some of them found shelter in the coastal city of Tartus.

The push by rebels in Hama province came days after they opened a new front against regime forces attacking checkpoints and army posts in the central region.

The new Eastern Orthodox Patriarch John X. Yaziji, who replaced Hazim, told reporters in the capital Damascus Saturday that the church is "deeply-rooted in Syria." He added that Christians in Syria are not part of the conflict and will continue to coexist with people of the region urging rival Syrian factions to negotiate a settlement through dialogue.

"We are staying here and this is our land," he said.

Activists and state media reported violence in different parts of Syria on Saturday including in the capital Damascus and the northern city of Aleppo, Syria's largest.

In Damascus, the state-run news agency SANA said gunmen assassinated Saturday Haider al-Sammoudi who works as a cameraman for the government's TV station. Several journalists working for state media have been assassinated over the past months.

In another development, 11 rebel groups said they have formed a new coalition, the Syrian Islamic Front.

A statement issued by the new group, dated Dec. 21 and posted on a militant website Saturday, described the group as "a comprehensive Islamic front that adopts Islam as a religion, doctrine, approach and conduct."

Several rebel groups have declared their own coalitions in Syria, including an "Islamic state" in the embattled city of Aleppo.

The statement said the new group will work to avoid differences or disputes with the other Islamic groups.

Syrian authorities meanwhile handed over to Beirut three Lebanese citizens who were killed last month in a clash with Syrian troops shortly after they crossed the border. Syria has so far returned 10 bodies to the Lebanese authorities and says it has no more.

____

Associated Press writer Maamoun Youssef in Cairo and Alblert Aji in Damascus contributed to this report.

Source: http://news.yahoo.com/rebels-threaten-storm-2-syrian-christian-towns-111223888.html

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Sunday, December 23, 2012

Relationships Initiate Self-Improvement ? Dr. Diva PhD Online ...

Relationships Initiate?Self-Improvement

Posted by Dr. Diva Verdun on December 21, 2012 ? Leave a Comment?

Looking at the way our relationships are structured we learn to use them as mirror reflections to find the things within ourselves that we need to focus our attention on.? As long as we are looking at the person that holds our affections with a critical eye, we are not focused on the reality that the reflection we see in the mirror is actually pointing at the issues we need to address within.

No matter how much we try to change someone else we cannot.? People only change when they find a reason to make improvements within and not before. By chastising and criticizing your beloved, you are actually driving a wedge into the relationship bond.? You are breaking down the bridge from which love freely flows.? Where you see they need to make self-improvement is also a marker that is pointing directly back to you, so that you can find the very same similarities within yourself.

Relationships are a slippery slope.? You can get so caught up in attempting to improve someone else?s behavior and character, that you are not even aware of your own.? A relationship can only level off to the height of your awareness of self.? Thus, if you are not aware of the internal struggles you are experiencing, you will continue to attract others into your experience that bring trials and challenges that are designed to point you in the direction of your own healing.

The miraculous thing about bonding relationships is the growth that both parties receive in the experience. When both people are working to improve themselves, the need to criticize and chastise each other falls away and becomes true deep loving support of each others individual and spiritual growth.

To often we want to control and force the other person into their healing to satisfy our own needs and fears.? The amazing thing about relationships is that the other person is limited in their growth and healing unless we are growing and healing as well.? Thus, no amount of force, pressure or control can move them one step forward in their own growth and healing.

If there is no growth and healing on an individual level, your relationship will become stagnant and dry-up resulting in either a break-up, because one person is growing and the other is not, or level off into a complacent and withered experience void of love and passion as the you both continue to simply co-exist in your pain.

Relationships Initiate Self-Improvement - Dr. Diva VerdunWhat you desire in a relationship is yours to have.? The person you attract to you is always right in the moment that they come into your experience.? They mirror exactly all you are at that particular moment, both the good and the bad.? Sadly, most people are not adept in many cases to be aware of this truth and don?t realize that the relationship is also mirroring your bad qualities as well, when you see them in your beloved.

Seeing yourself in the mirror of your relationship can be a beautiful experience when you see love, compassion, passion, trust, and all the other wonderful things that come with the union you are enjoying.? Sadly, you do not readily welcome seeing the bad.? However, when you begin to exercise self-mastery, you become aware that all things that happen for your bad, both big and small, in relationships and otherwise, are all designed for your good.? You become fully aware that your good manifest through you and you become disciplined to use every opportunity to work on your own issues, knowing that as you do everything else will level-off to your new state of awareness, including seeing growth and changes in your beloved and the relationship.

Relationships are not simply about love and passion and all the wonderful things that come with them.? They are key elements in your own growth in the equation of higher levels of awareness and spirituality. When you begin to exercise self-mastery to go deeper to carve out your own negative thinking and deal with your own pain, your behavior and character patterns change, which directly improve your relationship by either ending one that does not serve you, improving the one you have, as both people grow in Divine Love as Spirit makes the adjustments, or you begin to attract new people into your experience with fresh new mirrors.

Namaste!

Diva

Click here for a prayer treatment as you move into using your relationships for self-improvement

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Filed under Empowerment & Motivation, Exercising Independence, Love & Relationships, positive mental attitude, Spiritual ? Tagged with Acceptance, Achieving your dreams, divine power, divine presence, Dr Diva Phd, Empowerment, How to, infinite intelligence, Life, Life Coaching, lifestyle, living, living life, Love, love and relationships, love and relatioships, mental-health, Metaphysics, mirror reflections, mirrors, Motivation, Personal Development, positive spirituality, relationship mirrors, relationships, Self Help, Self-Esteem, self-improvement, self-mastery, Spiritual, spiritual mind treatment, spirituality, stop criticising your mate and look at yourself, Success, Success Coach

Source: http://drdivaphd.wordpress.com/2012/12/21/relationships-initiate-self-improvement/

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Source: http://fybegouo.posterous.com/relationships-initiate-self-improvement-dr-di

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Could 2013 Be The Year...

www.thenewyorkworld.com:

...Indian Point begins to power down?

Two months of Nuclear Regulatory Commission hearings on the future of the Indian Point Energy Center wrapped up last week, and though the license for one of the nuclear generators there is set to expire next fall ? with the other terminating in 2015 ? the practical reality is that the reactors can keep running until the commission decides whether to authorize their use for another 20 years at the request of their operator. It?s not operating under any deadline.

Read the whole story at www.thenewyorkworld.com

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Source: http://www.huffingtonpost.com/2012/12/22/could-2013-be-the-year_n_2351922.html

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Saturday, December 22, 2012

Unlocking new talents in nature

Friday, December 21, 2012

Protein engineers at the California Institute of Technology (Caltech) have tapped into a hidden talent of one of nature's most versatile catalysts. The enzyme cytochrome P450 is nature's premier oxidation catalyst?a protein that typically promotes reactions that add oxygen atoms to other chemicals. Now the Caltech researchers have engineered new versions of the enzyme, unlocking its ability to drive a completely different and synthetically useful reaction that does not take place in nature.

The new biocatalysts can be used to make natural products?such as hormones, pheromones, and insecticides?as well as pharmaceutical drugs, like antibiotics, in a "greener" way.

"Using the power of protein engineering and evolution, we can convince enzymes to take what they do poorly and do it really well," says Frances Arnold, the Dick and Barbara Dickinson Professor of Chemical Engineering, Bioengineering and Biochemistry at Caltech and principal investigator on a paper about the enzymes that appears online in Science. "Here, we've asked a natural enzyme to catalyze a reaction that had been devised by chemists but that nature could never do."

Arnold's lab has been working for years with a bacterial cytochrome P450. In nature, enzymes in this family insert oxygen into a variety of molecules that contain either a carbon-carbon double bond or a carbon-hydrogen single bond. Most of these insertions require the formation of a highly reactive intermediate called an oxene.

Arnold and her colleagues Pedro Coelho and Eric Brustad noted that this reaction has a lot in common with another reaction that synthetic chemists came up with to create products that incorporate a cyclopropane?a chemical group containing three carbon atoms arranged in a triangle. Cyclopropanes are a necessary part of many natural-product intermediates and pharmaceuticals, but nature forms them through a complicated series of steps that no chemist would want to replicate.

"Nature has a limited chemical repertoire," Brustad says. "But as chemists, we can create conditions and use reagents and substrates that are not available to the biological world."

The cyclopropanation reaction that the synthetic chemists came up with inserts carbon using intermediates called carbenes, which have an electronic structure similar to oxenes. This reaction provides a direct route to the formation of diverse cyclopropane-containing products that would not be accessible by natural pathways. However, even this reaction is not a perfect solution because some of the solvents needed to run the reaction are toxic, and it is typically driven by catalysts based on expensive transition metals, such as copper and rhodium. Furthermore, tweaking these catalysts to predictably make specific products remains a significant challenge?one the researchers hoped nature could overcome with evolution's help.

Given the similarities between the two reaction systems?cytochrome P450's natural oxidation reactions and the synthetic chemists' cyclopropanation reaction? Arnold and her colleagues argued that it might be possible to convince the bacterial cytochrome P450 to create cyclopropane-bearing compounds through this more direct route. Their experiments showed that the natural enzyme (cytochrome P450) could in fact catalyze the reaction, but only very poorly; it generated a low yield of products, didn't make the specific mix of products desired, and catalyzed the reaction only a few times. In comparison, transition-metal catalysts can be used hundreds of times.

That's where protein engineering came in. Over the years, Arnold's lab has created thousands of cytochrome P450 variants by mutating the enzyme's natural sequence of amino acids, using a process called directed evolution. The researchers tested variants from their collections to see how well they catalyzed the cyclopropane-forming reaction. A handful ended up being hits, driving the reaction hundreds of times.

Being able to catalyze a reaction is a crucial first step, but for a chemical process to be truly useful it has to generate high yields of specific products. Many chemical compounds exist in more than one form, so although the chemical formulas of various products may be identical, they might, for example, be mirror images of each other or have slightly different bonding structures, leading to dissimilar behavior. Therefore, being able to control what forms are produced and in what ratio?a quality called selectivity?is especially important.

Controlling selectivity is difficult. It is something that chemists struggle to do, while nature excels at it. That was another reason Arnold and her team wanted to investigate cytochrome P450's ability to catalyze the reaction.

"We should be able to marry the impressive repertoire of catalysts that chemists have invented with the power of nature to do highly selective chemistry under green conditions," Arnold says.

So the researchers further "evolved" enzyme variants that had worked well in the cyclopropanation reaction, to come up with a spectrum of new enzymes. And those enzymes worked?they were able to drive the reaction many times and produced many of the selectivities a chemist could desire for various substrates.

Coelho says this work highlights the utility of synthetic chemistry in expanding nature's catalytic potential. "This field is still in its infancy," he says. "There are many more reactions out there waiting to be installed in the biological world."

###

California Institute of Technology: http://www.caltech.edu

Thanks to California Institute of Technology for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/126058/Unlocking_new_talents_in_nature

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Remains of the Day: Instagram Amends its New Terms of Service

Remains of the Day: Instagram Amends its New Terms of ServiceInstagram reverts to its former advertising policy, an iOS patch may drain your battery, you can now search your online purchases via Google, and Amazon may offer its own version of Apple Care.

  • Updated Terms of Service Based on Your Feedback As a result of user feedback, Instagram has amended the Advertising section of its Terms of Service. Those guidelines will remain the same as they were in 2010, when the network launched. [Instagram Blog]
  • iOS 6.0.2 Suspected of Draining Batteries The latest iOS patch for iPhone 5 and iPad Mini released to amend a bug that had some users experience difficulty staying connected to Wi-Fi networks may have brought another problem with it. A few users are reporting that since updating, their iPhone's batteries have started to drain much faster than usual. However, some theorize that this is merely the software experiencing difficulty estimating actual power levels, and that letting it drain and recharging could solve the problem. [Ars Technica]
  • New Search Feature You can now search for online purchases that you've made via Google. Simply use the query [my purchases], and Google will search your Gmail for all of your orders. Since this feature?much like the already-active [my flights] query that allows you to search for tickets?essentially searches your inbox from the regular Search bar/page, you won't be able to use it unless you have a Gmail account. [Google+]
  • Is Amazon Working on its Own Version of AppleCare for Kindle products? A trademark application suggests that Amazon is looking to offer its own extended warranty service that uses language almost identical to Apple Care. The service would cover its Kindle devices, but the applications also hint at a full range of electronic hardware. [GigaOm]

Photo by photastic (Shutterstock), a2bb5s (Shutterstock), and Feng Yu (Shutterstock).

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/SNdCtiQNAqA/remains-of-the-day-instagram-amends-its-new-terms-of-service

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Obama on gun violence: 'We hear you.'

WASHINGTON (AP) ? President Barack Obama says his administration has received an outpouring of support for stricter gun laws following last week's elementary school massacre in Connecticut, telling respondents to an online petition, "We hear you."

The president said in a video released Friday that he has been encouraged that many gun owners have said there are steps the nation can take to prevent more deadly shootings, "steps that both protect our rights and protect our kids."

"I will do everything in my power as president to advance these efforts because if there's even one thing we can do as a country to protect our children, we have a responsibility to try," Obama said.

Obama was holding a moment of silence on Friday morning at the White House marking one week since the shooting that killed 20 children and six adults at a Newtown, Conn., elementary school. The National Rifle Association, the country's foremost gun lobby, was holding a news conference on Friday in the aftermath of the shootings.

The president has challenged the NRA to "do some self-reflection" and join a broad effort to reduce gun violence. The organization said Tuesday it would offer "meaningful contributions to help make sure this never happens again."

In Friday's video, the president responded to a "We the People" petition on the White House website that allows the public to submit petitions. Nearly 200,000 people have urged Obama to address gun control in one petition and petitions related to gun violence have amassed more than 400,000 signatures.

Obama has begun laying the groundwork for a push to tighten gun laws, address mental health needs and reexamine the glamorization of guns and violence.

Vice President Joe Biden is leading a working group of administration officials and outside advisers to offer recommendations by January. Biden's group is considering reinstating a ban on military-style assault weapons, which expired in 2004, closing loopholes that allow gun buyers to avoid background checks and restricting high-capacity magazines.

Gun-control measures have faced strong opposition in Congress for the past decade but Obama has suggested he intends to make it a key part of his agenda next year. In the video, he urged the public to become involved in

"If we're going to succeed, it's going to take a sustained effort of mothers and fathers, daughters and sons, law enforcement and responsible gun owners, organizing, speaking up, calling their members of Congress as many times as it takes, standing up and saying 'enough' on behalf of all our kids," Obama said.

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Online:

Obama response to petitions: http://www.youtube.com/watch?v=u5ynVMBxOus

http://www.youtube.com/watch?v=u5ynVMBxOus

Source: http://news.yahoo.com/obama-gun-violence-hear-110050167.html

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